ICD-10-CM > D50-D89 > D80-D89 > D89 > D89.8 > D89.83 D89.83 Cytokine release syndrome Non-Billable/Non-Specific Code First underlying cause, such as:complications following infusion, transfusion and therapeutic injection (T80.89-)complications of transplanted organs and tissue (T86.-) Use Additional code for adverse effect, if applicable, to identify immune checkpoint inhibitors and immunostimulant drugs (T45.AX5)code to identify associated manifestations Codes D89.831Cytokine release syndrome, grade 1D89.832Cytokine release syndrome, grade 2D89.833Cytokine release syndrome, grade 3D89.834Cytokine release syndrome, grade 4D89.835Cytokine release syndrome, grade 5D89.839Cytokine release syndrome, grade unspecified