ICD-10-CM>R00-R99>R50-R69>R65R65Symptoms and signs specifically associated with systemic inflammation and infectionNon-Billable/Non-SpecificCodesR65.1Systemic inflammatory response syndrome (SIRS) of non-infectious originR65.10Systemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunctionR65.11Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunctionR65.2Severe sepsisR65.20Severe sepsis without septic shockR65.21Severe sepsis with septic shock